Structure of PDB 4pw7 Chain A Binding Site BS02

Receptor Information
>4pw7 Chain A (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLV
LAGGFADEVDRGDEFTYTGSGGKKRIGAPSADQTLTNMNRALALNCDAPL
DDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWP
EISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pw7 Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Resolution2.001 Å
Binding residue
(original residue number in PDB)
H474 H479 R481 S482 R520
Binding residue
(residue number reindexed from 1)
H34 H39 R41 S42 R75
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:4pw7, PDBe:4pw7, PDBj:4pw7
PDBsum4pw7
PubMed24813944
UniProtQ96PU4|UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (Gene Name=UHRF2)

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