Structure of PDB 4pw6 Chain A Binding Site BS02
Receptor Information
>4pw6 Chain A (length=188) Species:
9606
(Homo sapiens) [
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IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLV
LAGGFADEVDRGDEFTYTGSSADQTLTNMNRALALNCDAPLDDKIGAESR
NWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFL
VWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
Ligand information
>4pw6 Chain D (length=12) [
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aacttcgatcac
Receptor-Ligand Complex Structure
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PDB
4pw6
Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Resolution
3.789 Å
Binding residue
(original residue number in PDB)
H474 H479 G480 R481 S482
Binding residue
(residue number reindexed from 1)
H34 H39 G40 R41 S42
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:4pw6
,
PDBe:4pw6
,
PDBj:4pw6
PDBsum
4pw6
PubMed
24813944
UniProt
Q96PU4
|UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (Gene Name=UHRF2)
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