Structure of PDB 4po7 Chain A Binding Site BS02

Receptor Information
>4po7 Chain A (length=658) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLV
IMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLT
AEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALST
ENGLWVSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALE
LWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGD
TWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIV
YSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGG
RWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPNAV
GIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIV
AIEHSSRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISI
WGFTESLTSQWVSYTIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCIL
GYKEQFLRLRKSSMCQNGRDYVVTKQPSICLCSLEDFLCDFGYYRPSKCV
EQPELKGHDLEFCLYGREEHLTTNGYRKIPGDKCQGGVNPVREVKDLKKK
CTSNFLSP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4po7 Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin.
Resolution2.66 Å
Binding residue
(original residue number in PDB)		H98 N130 E154 S156 G158 S159 R160 R163
Binding residue
(residue number reindexed from 1)		H46 N78 E102 S104 G106 S107 R108 R111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4po7, PDBe:4po7, PDBj:4po7
PDBsum4po7
PubMed24985322
UniProtQ99523|SORT_HUMAN Sortilin (Gene Name=SORT1)

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