Structure of PDB 4pjj Chain A Binding Site BS02

Receptor Information
>4pjj Chain A (length=743) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEE
DSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDI
PKIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGES
GAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNS
SRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCA
GASEDIRERLHLSSPDNFRYLNPLLDDHGDFIRMCTAMKKIGLDDEEKLD
LFRVVAGVLHLGNIDFEECNLKNKSTQALEYCAELLGLDQDDLRVSLTTM
VPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIA
GFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY
VDNQDCIDLIEARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLS
IPRKSKLAIHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESL
ICESRDKFIRELFESSLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKP
NLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKY
MPDKLARLDPRLFCKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMK
SDPDHLAELVKRVNHWLICSRWKKVQWCSLSVIKLKNKIKYRA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4pjj Chain A Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pjj How actin initiates the motor activity of Myosin.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		T158 S204
Binding residue
(residue number reindexed from 1)		T155 S201
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) S153 G154 T158 N200 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S150 G151 T155 N197 S200 S201 G401 E403
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4pjj, PDBe:4pjj, PDBj:4pjj
PDBsum4pjj
PubMed25936506
UniProtF1RQI7

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