Structure of PDB 4oe1 Chain A Binding Site BS02

Receptor Information

>4oe1 Chain A (length=687) Species: 4577 (Zea mays)

PDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHWEWA
LALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLD
VRAYTTVLHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMG
RSWPRIVALLDEMRAAGVEPDGFTASTVIAACSRDGLVDEAVAFFEDLKA
RGHAPCVVTYNALLQVFGKAGNYTEALRVLGEMEQNGCQPDAVTYNELAG
TEEAARCLDTMASPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPN
VNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNRVTWNTMLAVSGKRG
MEDYVTRVLEGMRSSGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSA
GFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQC
YAKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAF
QEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITY
NSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTVINGFCKQGLVK
EAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSEAREVIGYMVQHGLK
PMELTYRRVVESYCRAFEEARGFLSEVKALEAYIEDA

Ligand information

>4oe1 Chain C (length=14)

guauucauuauuuc

..............

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4oe1 Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10).
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): R175 T178 H182 V210 N213 R221 G245 F246 S249 T250 V281 N284 A285 Q288 V316 E320
• Binding residue (residue number reindexed from 1): R102 T105 H109 V137 N140 R148 G172 F173 S176 T177 V208 N211 A212 Q215 V243 E247
• Binding affinity: PDBbind-CN: Kd=1.25nM

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0042802 identical protein binding

Biological Process

• GO:0006397 mRNA processing
• GO:0048255 mRNA stabilization

Cellular Component

• GO:0009507 chloroplast
• GO:0009570 chloroplast stroma

External links

• PDB: RCSB:4oe1, PDBe:4oe1, PDBj:4oe1
• PDBsum: 4oe1
• PubMed: 25231995
• UniProt: B8Y6I0|PPR10_MAIZE Pentatricopeptide repeat-containing protein 10, chloroplastic (Gene Name=PPR10)