Structure of PDB 4o4z Chain A Binding Site BS02

Receptor Information
>4o4z Chain A (length=148) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSP
EDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVR
LSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG
Ligand information
Ligand IDN2O
InChIInChI=1S/N2O/c1-2-3
InChIKeyGQPLMRYTRLFLPF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		[O-][N+]#N
OpenEye OEToolkits 1.5.0N#[N+][O-]
FormulaN2 O
NameNITROUS OXIDE;
NITROGEN OXIDE
ChEMBLCHEMBL1234579
DrugBankDB06690
ZINC
PDB chain4o4z Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4o4z Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence for Protein-dependent Processes in the Mechanisms of General Anesthesia
Resolution1.7 Å
Binding residue
(original residue number in PDB)		F28 S55 L56
Binding residue
(residue number reindexed from 1)		F26 S53 L54
Annotation score1
Enzymatic activity
Enzyme Commision number 1.7.-.-
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4o4z, PDBe:4o4z, PDBj:4o4z
PDBsum4o4z
PubMed25211169
UniProtQ9ER97|NGB_MOUSE Neuroglobin (Gene Name=Ngb)

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