Structure of PDB 4ngf Chain A Binding Site BS02

Receptor Information
>4ngf Chain A (length=260) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPH
FPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRYCVLPL
NVVSTLDIDFKFMEDIEKSETKETPFVFKLEDYQDAVIIPRYRNFDQPHR
FYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTS
SRLNLLTPRPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVC
LPSILYRLHC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ngf A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Resolution3.101 Å
Binding residue
(original residue number in PDB)		Y926 R927 F950 S952 F958 Y961 Y962 K965 Y966 S1006 R1010 W1014 L1017 Q1021 I1022
Binding residue
(residue number reindexed from 1)		Y142 R143 F166 S168 F174 Y177 Y178 K181 Y182 S213 R217 W221 L224 Q228 I229
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4ngf, PDBe:4ngf, PDBj:4ngf
PDBsum4ngf
PubMed24486018
UniProtQ9UPY3|DICER_HUMAN Endoribonuclease Dicer (Gene Name=DICER1)

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