Structure of PDB 4n47 Chain A Binding Site BS02 |
| >4n47 Chain A (length=666) Species: 274 (Thermus thermophilus)
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GKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVARRAG
GVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPKDPG
ERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAVLD
LWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTWEL
LRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPRKPI
PHLTGLLVPVLTLEDLSLPWEERRRRTREIASWIGRRLGLGTPEAVRAQA
YRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRLDGAQGWPEFLRR
ALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEEGVQAVLVLTPPM
AWEDRNRLKALLLREGLPSQILNVPLREEERHRWENALLGLLAKAGLQVV
ALSGAYPAELAVGFDAGGRESFRFGGAACAVGGHLLWTLPEAERIPQEVV
WDLLEETLWAFRRKAGRLPSRVLLLRDGRVPQDEFALALEALAREGIAYD
LVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVHRDFRGTPRPLKL
VHEAGDTPLEALAHQIFHLTRLYPASGFAFPRLPAPLHLADRLVKEVGRL
GIRHLKEVDREKLFFV |
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| PDB | 4n47 Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. |
| Resolution | 2.823 Å |
Binding residue
(original residue number in PDB) | A170 Y171 R172 I173 Y197 T201 L217 Y226 H227 R232 I254 P255 L265 R286 P412 M413 W415 K422 Q433 I434 N436 R446 N449 K457 R580 R611 T613 P614 Y642 S645 A648 P650 R651 H657 V685 |
Binding residue
(residue number reindexed from 1) | A166 Y167 R168 I169 Y193 T197 L213 Y222 H223 R228 I250 P251 L261 R273 P399 M400 W402 K409 Q420 I421 N423 R433 N436 K444 R561 R592 T594 P595 Y623 S626 A629 P631 R632 H638 V666 |
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