Structure of PDB 4l76 Chain A Binding Site BS02

Receptor Information
>4l76 Chain A (length=227) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKSRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHG
DPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAQ
RYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTR
RMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSF
RAGDIILGIGKPEEIERLKNYISALVP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4l76 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4l76 Structural basis of allosteric interactions among Ca(2+)-binding sites in a K(+) channel RCK domain.
Resolution2.992 Å
Binding residue
(original residue number in PDB)		G290 E326
Binding residue
(residue number reindexed from 1)		G178 E214
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
Biological Process
GO:0006813 potassium ion transport

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Molecular Function
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Biological Process
External links
PDB RCSB:4l76, PDBe:4l76, PDBj:4l76
PDBsum4l76
PubMed24126388
UniProtO27564|MTHK_METTH Calcium-gated potassium channel MthK (Gene Name=mthK)

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