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Receptor Information

>4k8z Chain A (length=756) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEE
VKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKI
REHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKE
KDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWE
TGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIP
SLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYA
RARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPG
ADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEE
GKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKL
SKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVIS
YIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGY
RKEDLR

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4k8z Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex
Resolution	2.29 Å
Binding residue (original residue number in PDB)	N269 D540 K592 Y594 R606 G607 V611 R612 R613 Q665 T667 R668 Y673 K674 A675 H679
Binding residue (residue number reindexed from 1)	N269 D540 K592 Y594 R606 G607 V611 R612 R613 Q665 T667 R668 Y673 K674 A675 H679

Enzyme Commision number

2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-

	Molecular Function
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity

PDB	RCSB:4k8z, PDBe:4k8z, PDBj:4k8z
PDBsum	4k8z
PubMed	23733496
UniProt	P77933\|DPOL_THEKO DNA polymerase (Gene Name=pol)

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Structure of PDB 4k8z Chain A Binding Site BS02