Structure of PDB 4jiz Chain A Binding Site BS02

Receptor Information
>4jiz Chain A (length=172) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSA
GPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVP
FPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFF
VQEFNLIDRRELAPLQELIEKL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4jiz Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4jiz Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C58 C63 H140 H145
Binding residue
(residue number reindexed from 1)		C40 C45 H122 H127
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4jiz, PDBe:4jiz, PDBj:4jiz
PDBsum4jiz
PubMed23579499
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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