Structure of PDB 4jej Chain A Binding Site BS02

Receptor Information
>4jej Chain A (length=241) Species: 376686 (Flavobacterium johnsoniae UW101) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KILTTIHQQILEAKKNGQKLLAILLDPDKIVWENLDHLLLKINQSPATHI
FVGGSIVESTIIEDLIAQLKQKTRLPVVIFPGDPSQISPKADAILFLSLL
SGRNPDYLIEYQVQAAPILKKTNLEVISTGYILIESGNETAVARVSKTEP
LNRENFDLALATAQAGEMLGSKLIYLEAGSGAKKPVPLEMISVISQNVEI
PIIVGGGIVDLHGIKKAYNAGADLVVIGTAFENDSHFFDSL
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain4jej Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4jej A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
Resolution1.52 Å
Binding residue
(original residue number in PDB)		R106 T151 E152
Binding residue
(residue number reindexed from 1)		R103 T148 E149
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.41: phosphoglycerol geranylgeranyltransferase.
Gene Ontology
Molecular Function
GO:0000107 imidazoleglycerol-phosphate synthase activity
GO:0000287 magnesium ion binding
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
GO:0047294 phosphoglycerol geranylgeranyltransferase activity
Biological Process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jej, PDBe:4jej, PDBj:4jej
PDBsum4jej
PubMed24684232
UniProtA5FJK8|GGGPS_FLAJ1 Geranylgeranylglyceryl phosphate synthase (Gene Name=Fjoh_1584)

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