Structure of PDB 4iwy Chain A Binding Site BS02

Receptor Information
>4iwy Chain A (length=294) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSI
HYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARAR
DKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQG
IGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVV
AAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVD
ILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATT
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain4iwy Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4iwy Structure and function of Escherichia coli RimK, an ATP-grasp fold, l-glutamyl ligase enzyme.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		R102 L106 R109
Binding residue
(residue number reindexed from 1)		R104 L108 R111
Annotation score4
Enzymatic activity
Enzyme Commision number 6.3.2.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
GO:0016874 ligase activity
GO:0018169 ribosomal S6-glutamic acid ligase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0009432 SOS response
GO:0018410 C-terminal protein amino acid modification
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4iwy, PDBe:4iwy, PDBj:4iwy
PDBsum4iwy
PubMed23609986
UniProtP0C0U4|RIMK_ECOLI Ribosomal protein bS6--L-glutamate ligase (Gene Name=rimK)

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