Structure of PDB 4hdu Chain A Binding Site BS02

Receptor Information
>4hdu Chain A (length=108) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRMDEFYTKVYDAVCEIPYGKVSTYGEIARYVGMPSYARQVGQAMKHLHP
ETHVPWHRVINSRGTISKRDISAGEQRQKDRLEEEGVEIYQTSLGEYKLN
LPEYMWKP
Ligand information
Receptor-Ligand Complex Structure
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PDB4hdu Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions.
Resolution2.848 Å
Binding residue
(original residue number in PDB)		M3 S36 Y37 Q40
Binding residue
(residue number reindexed from 1)		M3 S36 Y37 Q40
Binding affinityPDBbind-CN: Kd=9.3nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003824 catalytic activity
GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0032132 O6-alkylguanine-DNA binding
Biological Process
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0070911 global genome nucleotide-excision repair
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hdu, PDBe:4hdu, PDBj:4hdu
PDBsum4hdu
PubMed23112169
UniProtQ9UTN9|ATL1_SCHPO Alkyltransferase-like protein 1 (Gene Name=atl1)

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