Structure of PDB 4h2r Chain A Binding Site BS02

Receptor Information
>4h2r Chain A (length=369) Species: 266835 (Mesorhizobium japonicum MAFF 303099) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRRAEVAGGGFAGLTAAIALKQNGWDVRLHEKSSELRAFGAGIYLWHNGL
RVLEGLGALDDVLQGSHTPPTYETWMHNKSVSKETFNGLPWRIMTRSHLH
DALVNRARALGVDISVNSEAVAADPVGRLTLQTGEVLEADLIVGADGVGS
KVRDSIGFKQDRWVSKDGLIRLIVPRMKKELGHGEWDNTIDMWNFWPRVQ
RILYSPCNENELYLGLMAPAADPRGSSVPIDLEVWVEMFPFLEPCLIEAA
KLKTARYDKFETTKLDSWTRGKVALVGDAAHAMCPALAQGAGCAMVNAFS
LSQDLEEGSSVEDALVAWETRIRPITDRCQALSGDYAANRSLSKGNMFTP
AALEAARYDPLRRVYSWPQ
Ligand information
Ligand ID5HN
InChIInChI=1S/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10)
InChIKeyATTDCVLRGFEHEO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370Oc1cncc(c1)C(O)=O
ACDLabs 12.01O=C(O)c1cncc(O)c1
OpenEye OEToolkits 1.7.6c1c(cncc1O)C(=O)O
FormulaC6 H5 N O3
Name5-hydroxypyridine-3-carboxylic acid;
5-Hydroxynicotinic Acid
ChEMBLCHEMBL2146902
DrugBank
ZINCZINC000000332673
PDB chain4h2r Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4h2r Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
Resolution2.473 Å
Binding residue
(original residue number in PDB)		R211 L213
Binding residue
(residue number reindexed from 1)		R201 L203
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.12.4: Transferred entry: 1.14.13.242.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004497 monooxygenase activity
GO:0071949 FAD binding

View graph for
Molecular Function
External links
PDB RCSB:4h2r, PDBe:4h2r, PDBj:4h2r
PDBsum4h2r
PubMed
UniProtQ988D3

[Back to BioLiP]