Structure of PDB 4g1p Chain A Binding Site BS02

Receptor Information
>4g1p Chain A (length=479) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSHSLTSVFQKIDSLKPQFFSRLTKAIQIPAVSSDESLRSKVFDKAKFIS
EQLSQSGFHDIKMVDLGIQPPPSTPNLSLPPVILSRFGSDPSKKTVLVYG
HYDVQPAQLEDGWDTEPFKLVIDEAKGIMKGRGVTDDTGPLLSWINVVDA
FKASGQEFPVNLVTCFEGMEESGSLKLDELIKKEANGYFKGVDAVCISDN
YWLGTKKPVLTYGLRGCNYYQTIIEGPSADLHSGIFGGVVAEPMIDLMQV
LGSLVDSKGKILIDGIDEMVAPLTEKEKALYKDIEFSVEELNAATGSKTS
LYDKKEDILMHRWRYPSLSIHGVEGAFSAQGAKTVIPAKVFGKFSIRTVP
DMDSEKLTSLVQKHCDAKFKSLNSPNKCRTELIHDGAYWVSDPFNAQFTA
AKKATKLVYGVDPDFTREGGSIPITLTFQDALNTSVLLLPMGRGDDGAHS
INEKLDISNFVGGMKTMAAYLQYYSESPE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4g1p Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4g1p Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae
Resolution2.547 Å
Binding residue
(original residue number in PDB)		D137 D200
Binding residue
(residue number reindexed from 1)		D136 D199
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.13.-
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008242 omega peptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070573 metallodipeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006751 glutathione catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4g1p, PDBe:4g1p, PDBj:4g1p
PDBsum4g1p
PubMed
UniProtP43616|DUG1_YEAST Cys-Gly metallodipeptidase DUG1 (Gene Name=DUG1)

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