Structure of PDB 4fmo Chain A Binding Site BS02

Receptor Information
>4fmo Chain A (length=264) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVNVNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDL
KLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFD
ELNDDASKEKIISKIWDMSSMLNEYYSIELVNDGLDNDLKSVKLKSLPLL
LKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMVPKV
DTSDASLSEDEKAQFINRKEHISSLLEHVLFPCIKRRFLAPRHILKDVVE
IANLPDLYKVFERC
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4fmo Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4fmo Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Resolution3.04 Å
Binding residue
(original residue number in PDB)		D531 H553
Binding residue
(residue number reindexed from 1)		D26 H48
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0032300 mismatch repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4fmo, PDBe:4fmo, PDBj:4fmo
PDBsum4fmo
PubMed23435383
UniProtP38920|MLH1_YEAST DNA mismatch repair protein MLH1 (Gene Name=MLH1)

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