Structure of PDB 4flv Chain A Binding Site BS02

Receptor Information
>4flv Chain A (length=757) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HAGMIIDADYITEDGKPIIRIFKKEKGEFKVEYDRTFRPYIYALLKDDSA
IDEVKKITAERHGKIVRITEVEKVQKKFLGRPIEVWKLYLEHPQDVPAIR
EKIREHPAVVDIFEYDIPFAKRYLIDKGLTPMEGNEELTFLAVDIETLYH
EGEEFGKGPIIMISYADEEGAKVITWKSIDLPYVEVVSSEREMIKRLVKV
IREKDPDVIITYNGDNFAFPYLLKRAEKLGIKLPLGRDNSEPKMQRMGDS
LAVEIKGRIHFDLFPVIRRTINLPTYTLEAVYEAIFGKSKEKVYAHEIAE
AWETGKGLERVAKYSMEDAKVTFELGKEFFPMEAQLARLVGQPVWDVSRS
STGNLVEWFLLRKAYERNELAPNKPDEREYERRLRESYEGKEPEKGLWEG
IVSLDFRSLYPSIIITHNVSPDTLNRENCKEYDVAPQVGHRFCKDFPGFI
PSLLGNLLEERQKIKKRMKESKDPVEKKLLDYRQRAIKILANSYYGYYGY
AKARWYCKECAESVTAWGRQYIDLVRRELESRGFKVLYIDTDGLYATIPG
AKHEEIKEKALKFVEYINSKLPGLLELEYEGFYARGFFVTKKKYALIDEE
GKIVTRGLEIVRRDWSEIAKETQAKVLEAILKHGNVDEAVKIVKEVTEKL
SKYEIPPEKLVIYEQITRPLSEYKAIGPHVAVAKRLAAKGVKVKPGMVIG
YIVLRGDGPISKRAIAIEEFDPKKHKYDAEYYIENQVLPAVERILRAFGY
RKEDLKY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4flv Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y7 Y37 P90 Q91 V93 P94 R97 E111 D113 I114 P115 F116 K118 R119 K240 G245 D246 R265 N351 W355 K371 Y500 K593 W615 A675 I676 I710 S711 Y731 R743
Binding residue
(residue number reindexed from 1)		Y10 Y40 P93 Q94 V96 P97 R100 E114 D116 I117 P118 F119 K121 R122 K243 G248 D249 R268 N354 W358 K374 Y500 K593 W615 A675 I676 I710 S711 Y731 R743
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4flv, PDBe:4flv, PDBj:4flv
PDBsum4flv
PubMed22902479
UniProtP0CL77|DPOL_PYRAB DNA polymerase 1 (Gene Name=polI)

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