Structure of PDB 4f50 Chain A Binding Site BS02

Receptor Information
>4f50 Chain A (length=337) Species: 273057,330779 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYSSGAVATANYEARKLGV
KAGMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIEVASID
EAYLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKILAKII
ADKSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGIQKLRD
ILSKNYNELEKITGKAKALYLLKLAQNKYSEPVENKSKIPHGRIVTMKRN
SRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPH
GISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI
Ligand information
Receptor-Ligand Complex Structure
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PDB4f50 Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.215 Å
Binding residue
(original residue number in PDB)		M59 P60 K63 K220 K340
Binding residue
(residue number reindexed from 1)		M54 P55 K58 K215 K335
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4f50, PDBe:4f50, PDBj:4f50
PDBsum4f50
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

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