Structure of PDB 4f4y Chain A Binding Site BS02

Receptor Information
>4f4y Chain A (length=343) Species: 273057,330779 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYSGRTKTSGAVATANYEA
RKLGVKAGMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIE
VASIDEAYLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKI
LAKIIADKSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGI
QKLRDILSKNYNELEKITGKAKALYLLKLAQDEYNEPIRTRVRKSIGRYL
TLPYNTRDVKVILPYLKKAINEAYNKVNGIPMRITVIAIMEDLDILSKGK
KFKHGISIDNAYKVAEDLLRELLVRDKRRNVRRIGVKLDNIII
Ligand information
Receptor-Ligand Complex Structure
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PDB4f4y Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.338 Å
Binding residue
(original residue number in PDB)		V32 S34 G41 A42 P60 I62 K63 K78 K220 A221 R243 K244 S245 I246 G247 R248 Y249 T251 L293 R332 R333
Binding residue
(residue number reindexed from 1)		V32 S34 G41 A42 P60 I62 K63 K78 K220 A221 R243 K244 S245 I246 G247 R248 Y249 T251 L293 R332 R333
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4f4y, PDBe:4f4y, PDBj:4f4y
PDBsum4f4y
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

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