Structure of PDB 4f4x Chain A Binding Site BS02

Receptor Information
>4f4x Chain A (length=342) Species: 273057,330779 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYSGRTKTSGAVATANYEA
RKLGVKAGMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIE
VASIDEAYLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKI
LAKIIADKSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGI
QKLRDILSKNYNELEKITGKAKALYLLKLAQDEYNEPIRTRVRKSIGRIV
TMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRG
RTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI
Ligand information
Receptor-Ligand Complex Structure
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PDB4f4x Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.049 Å
Binding residue
(original residue number in PDB)		V32 S34 G41 A42 P60 I62 Q66 A221 K222 R241 V242 R243 K244 S245 G247 R248 I249 T251 L294 R332 R333 R337
Binding residue
(residue number reindexed from 1)		V32 S34 G41 A42 P60 I62 Q66 A221 K222 R241 V242 R243 K244 S245 G247 R248 I249 T251 L294 R332 R333 R337
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4f4x, PDBe:4f4x, PDBj:4f4x
PDBsum4f4x
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

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