Structure of PDB 4ee1 Chain A Binding Site BS02

Receptor Information
>4ee1 Chain A (length=321) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERG
IGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMF
PLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIR
KLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITL
MFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFT
TFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQ
KAINDVAPFFNVSPEQLANEI
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4ee1 Chain A Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ee1 Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		D310 D343
Binding residue
(residue number reindexed from 1)		D203 D236
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.101: DNA primase DnaG.
Gene Ontology
Molecular Function
GO:0003896 DNA primase activity
Biological Process
GO:0006269 DNA replication, synthesis of primer

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Molecular Function
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Biological Process
External links
PDB RCSB:4ee1, PDBe:4ee1, PDBj:4ee1
PDBsum4ee1
PubMed22795082
UniProtO05338|DNAG_STAAU DNA primase (Gene Name=dnaG)

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