Structure of PDB 4e7k Chain A Binding Site BS02

Receptor Information
>4e7k Chain A (length=366) Species: 11963 (Human spumaretrovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DAELDQLLQGHYIKGYPKQYTYFLEDGKVKVSRPEGVKIIPPQSDRQKIV
LQAHNLAHTGREATLLKIANLYWWPNMRKDVVKQLGRCQQCLITNASNKA
SGPILRPDRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPT
KAPSTSATVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEF
STPYHPQSSGKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYS
PVLKYTPHQLLFGIDSNTPFANQDTLDLTREEELSLLQEIRTSLYHPSTP
PASSRSWSPVVGQLVQERVARPASLRPRWHKPSTVLKVLNPRTVVILDHL
GNNRTVSIDNLKPTSH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4e7k 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo.
Resolution3.02 Å
Binding residue
(original residue number in PDB)		P214 E221 K228 K262
Binding residue
(residue number reindexed from 1)		P206 E213 K220 K254
Enzymatic activity
Catalytic site (original residue number in PDB) D128 D185 E221
Catalytic site (residue number reindexed from 1) D120 D177 E213
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:4e7k, PDBe:4e7k, PDBj:4e7k
PDBsum4e7k
PubMed22580823
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

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