Structure of PDB 4d2b Chain A Binding Site BS02

Receptor Information
>4d2b Chain A (length=445) Species: 264199 (Streptococcus thermophilus LMG 18311) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRAT
AASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALP
FGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGI
NLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHY
LRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTI
VAIAIPVFYFAWMISLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERV
DSSWFPVSWFQSLNPLFIMLYTPFFAWLWTANQPSSPTKFAVGLMFAGLS
FLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTMMSMW
FLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLS
Ligand information
Ligand ID78M
InChIInChI=1S/C18H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18(21)22-16-17(20)15-19/h8-9,17,19-20H,2-7,10-16H2,1H3/b9-8-/t17-/m0/s1
InChIKeyBJMLBVHMHXYQFS-JJEJIETFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6CCCCCCCC=CCCCCCC(=O)OCC(CO)O
ACDLabs 12.01O=C(OCC(O)CO)CCCCC\C=C/CCCCCCC
OpenEye OEToolkits 1.7.6CCCCCCC/C=C\CCCCCC(=O)OC[C@H](CO)O
CACTVS 3.370CCCCCCCC=CCCCCCC(=O)OC[CH](O)CO
CACTVS 3.370CCCCCCC\C=C/CCCCCC(=O)OC[C@@H](O)CO
FormulaC18 H34 O4
Name(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE;
7.8 MONOACYLGLYCEROL
ChEMBL
DrugBank
ZINCZINC000098208564
PDB chain4d2b Chain A Residue 1474 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4d2b Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		I234 M238 A248 I255 F263
Binding residue
(residue number reindexed from 1)		I229 M233 A243 I250 F258
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0006857 oligopeptide transport
GO:0015833 peptide transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4d2b, PDBe:4d2b, PDBj:4d2b
PDBsum4d2b
PubMed24916388
UniProtQ5M4H8

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