Structure of PDB 4chu Chain A Binding Site BS02

Receptor Information
>4chu Chain A (length=126) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRL
RKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDKSLTHALWRDL
SDRLTGFLNNITLGELVNNQEVLDVS
Ligand information
Receptor-Ligand Complex Structure
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PDB4chu The Unique Regulation of Iron-Sulfur Cluster Biogenesis in a Gram-Positive Bacterium.
Resolution2.489 Å
Binding residue
(original residue number in PDB)		P27 E43 R50 S57 R59 P61 G64 Y65
Binding residue
(residue number reindexed from 1)		P28 E44 R51 S58 R60 P62 G65 Y66
Binding affinityPDBbind-CN: Kd=180nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005506 iron ion binding
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4chu, PDBe:4chu, PDBj:4chu
PDBsum4chu
PubMed24847070
UniProtC3SZN7

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