Structure of PDB 4c9d Chain A Binding Site BS02

Receptor Information
>4c9d Chain A (length=262) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKPFT
LAPLPGPEGATLKGTLRLRLTTLDDGLFAPFLRALLEAAPDGLPLGDSSY
RLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGR
TRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFR
NLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGA
KTPYGMGLAVPL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4c9d Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		E197 W228
Binding residue
(residue number reindexed from 1)		E195 W226
Binding affinityPDBbind-CN: Kd=3.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:4c9d, PDBe:4c9d, PDBj:4c9d
PDBsum4c9d
PubMed24150936
UniProtQ53VU8

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