Structure of PDB 4bxd Chain A Binding Site BS02

Receptor Information

>4bxd Chain A (length=255) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLTIDYNSYRTTTPYGKRVRFLVLHYTALDFAASVKALTTGAASAHYLIP
APHDPSYKAAGFKGQRIFNLVAEEDRAWHAGVSGWARRDNLNDTSIGIEI
VNLARDDDGVFTFPDYERSQINALKQLAKNILQRYPDMTPKNVVGHSDIA
VGRKSDPGPKLPWKELYEAGIGAWYDDATRDRYREGFERDGLPPRADLLE
AFRLYGYALPATVDDAYFASLLRAFQMHFRPENYDGALDVETAAILYALN
EKYPA

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

4bxd Chain A Residue 1260 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4bxd Cell-Wall Remodeling by the Zinc-Protease Ampdh3 from Pseudomonas Aeruginosa.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	H25 H146
Binding residue (residue number reindexed from 1)	H25 H146
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.5.1.28: N-acetylmuramoyl-L-alanine amidase.

Gene Ontology

	Molecular Function
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0009253	peptidoglycan catabolic process
GO:0009254	peptidoglycan turnover
GO:0071555	cell wall organization

	Cellular Component
GO:0009276	Gram-negative-bacterium-type cell wall
GO:0019867	outer membrane

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External links

PDB	RCSB:4bxd, PDBe:4bxd, PDBj:4bxd
PDBsum	4bxd
PubMed	23931161
UniProt	Q9I5D1

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