Structure of PDB 4boc Chain A Binding Site BS02

Receptor Information
>4boc Chain A (length=989) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAV
MLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIE
RCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPP
VNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSV
EKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSL
YPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQ
RVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEELGAPEALREQPW
PLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGI
LKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKL
MRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQL
FQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAR
EMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDV
ARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDD
ILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVH
QDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQD
AQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDF
PQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEW
VTPLGVPVIQPYRLDSRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYR
KGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRF
CSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4boc Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Resolution2.65 Å
Binding residue
(original residue number in PDB)		S611 R613 N614 I618 K767 E771 S774 L775 L816 G817 S818 R822 M995 K1012 D1151
Binding residue
(residue number reindexed from 1)		S391 R393 N394 I398 K547 E551 S554 L555 L596 G597 S598 R602 M775 K792 D910
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4boc, PDBe:4boc, PDBj:4boc
PDBsum4boc
PubMed24096365
UniProtO00411|RPOM_HUMAN DNA-directed RNA polymerase, mitochondrial (Gene Name=POLRMT)

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