Structure of PDB 4bdv Chain A Binding Site BS02

Receptor Information
>4bdv Chain A (length=612) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATRRYYLGAVELSWDYVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQ
AEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDK
VFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALL
VCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSPKMHTVNGYVNRSLPGL
IGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLT
AQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPKHPKTWVHYIAA
EEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKT
REAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYS
RRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVN
MERDLASGLIGPLLICYKERNVILFSVFDENRSWYLTENIQRFLPNPAGV
QLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSV
FFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRG
MTALLKVSSCDK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4bdv Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bdv Evaluation of the Metal Binding Sites in a Recombinant Coagulation Factor Viii Identifies Two Sites with Unique Metal Binding Properties.
Resolution3.98 Å
Binding residue
(original residue number in PDB)		K107 D116 D125 D126
Binding residue
(residue number reindexed from 1)		K80 D89 D98 D99
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding

View graph for
Molecular Function
External links
PDB RCSB:4bdv, PDBe:4bdv, PDBj:4bdv
PDBsum4bdv
PubMed23435097
UniProtP00451|FA8_HUMAN Coagulation factor VIII (Gene Name=F8)

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