Structure of PDB 4b92 Chain A Binding Site BS02

Receptor Information
>4b92 Chain A (length=476) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGK
LVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE
TSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNS
FQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEAL
DLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDV
IAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNT
STYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMS
VIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWD
PEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAE
GTGKFCPLRSFPDTVYKKLVQREKTL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4b92 Chain A Residue 1484 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4b92 Insights Into the Oligomerization of Crmps: Crystal Structure of Human Collapsin Response Mediator Protein 5.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H282 H290
Binding residue
(residue number reindexed from 1)		H276 H284
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4b92, PDBe:4b92, PDBj:4b92
PDBsum4b92
PubMed23373749
UniProtQ9BPU6|DPYL5_HUMAN Dihydropyrimidinase-related protein 5 (Gene Name=DPYSL5)

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