Structure of PDB 4b8o Chain A Binding Site BS02

Receptor Information
>4b8o Chain A (length=422) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRFVQ
FLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSD
DVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNAT
WTLSNFCRGKPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDG
TNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCI
IDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIG
PLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDLLI
CPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIEN
LQSHDNNEIYEKAVKILEAYWM
Ligand information
Receptor-Ligand Complex Structure
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PDB4b8o Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Resolution2.084 Å
Binding residue
(original residue number in PDB)		G272 V312 T313 G314 W349 N353 A356 E388 W391 N395
Binding residue
(residue number reindexed from 1)		G200 V240 T241 G242 W277 N281 A284 E316 W319 N323
Enzymatic activity
Catalytic site (original residue number in PDB) T147 A159 N353 N358 K359
Catalytic site (residue number reindexed from 1) T75 A87 N281 N286 K287
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4b8o, PDBe:4b8o, PDBj:4b8o
PDBsum4b8o
PubMed23250448
UniProtQ71VM4|IMA1A_ORYSJ Importin subunit alpha-1a (Gene Name=Os01g0253300)

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