Structure of PDB 4b5h Chain A Binding Site BS02

Receptor Information
>4b5h Chain A (length=259) Species: 487 (Neisseria meningitidis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLKIISANVNGIRSAYKKGFYEYIAASGTDIVCVQELKAQEADLSADMKN
PHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDF
GRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGNW
NIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVP
GYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPL
VVEYDYAAE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4b5h Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Resolution3.05 Å
Binding residue
(original residue number in PDB)		G11 R13 S14 K18 K38 R64 G65 N207 R208
Binding residue
(residue number reindexed from 1)		G11 R13 S14 K18 K38 R64 G65 N207 R208
Enzymatic activity
Catalytic site (original residue number in PDB) N8 N10 E36 Y109 N149 N151 D221 D246 H247
Catalytic site (residue number reindexed from 1) N8 N10 E36 Y109 N149 N151 D221 D246 H247
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004518 nuclease activity
GO:0008081 phosphoric diester hydrolase activity
GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4b5h, PDBe:4b5h, PDBj:4b5h
PDBsum4b5h
PubMed23035246
UniProtQ7DD47

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