Structure of PDB 4ayx Chain A Binding Site BS02

Receptor Information
>4ayx Chain A (length=571) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNP
TVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFS
SILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVG
ISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQL
AEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATG
LSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYS
ELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPA
RPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISL
DGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI
QRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPK
ILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAV
LDQGKITEYGKHEELLSKPNG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4ayx Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ayx Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S534 Q575
Binding residue
(residue number reindexed from 1)		S381 Q422
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ayx, PDBe:4ayx, PDBj:4ayx
PDBsum4ayx
PubMed23716676
UniProtQ9NRK6|ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial (Gene Name=ABCB10)

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