Structure of PDB 4am3 Chain A Binding Site BS02

Receptor Information
>4am3 Chain A (length=622) Species: 190650 (Caulobacter vibrioides CB15) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMFDIKRKTIEWGGKTLVLETGRIARQADGAVLATMGETVVLATAVFAK
SQKPGQDFFPLTVNYQEKTFAAGKIPGGFFKREGRPSEKETLVSRLIDRP
IRPLFVKGFKNEVQVVVTVLQHDLENDPDILGMVAASAALCLSGAPFMGP
IGAARVGWVDGAYVLNPTLDEMKESKMDLVVAGTADAVMMVESEIQELSE
EIVLGGVNFAHQQMQAVIDAIIDLAEHAAKEPFAFEPEDTDAIKAKMKDL
VGADIAAAYKIQKKQDRYEAVGAAKKKAIAALGLSDENPTGYDPLKLGAI
FKELEADVVRRGILDTGLRIDGRDVKTVRPILGEVGILPRTHGSALFTRG
ETQAIVVATLGTGDDEQFIDALEGTYKESFLLHYNFPPYSVGETGRMGSP
GRREIGHGKLAWRALRPMLPTKEDFPYTIRLVSEITESNGSSSMATVCGS
SLAMMDAGVPLVRPVSGIAMGLILEQDGFAVLSDILGDEDHLGDMDFKVA
GTSEGLTSLQMDIKIAGITPAIMEQALAQAKEGRAHILGEMNKAMDAPRA
DVGDFAPKIETINIPTDKIREVIGSGGKVIREIVATTGAKVDINDDGVVK
VSASDGAKIKAAIDWIKSITDE
Ligand information
Receptor-Ligand Complex Structure
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PDB4am3 Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D368 R568 I571 S573 G574 G575 I578
Binding residue
(residue number reindexed from 1)		D370 R570 I573 S575 G576 G577 I580
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4am3, PDBe:4am3, PDBj:4am3
PDBsum4am3
PubMed22724061
UniProtQ9AC32|PNP_CAUVC Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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