Structure of PDB 3zdc Chain A Binding Site BS02

Receptor Information
>3zdc Chain A (length=247) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDD
ESSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEA
DDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPF
IDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGI
YENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain3zdc Chain A Residue 1251 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zdc The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Resolution1.53 Å
Binding residue
(original residue number in PDB)		L171 A172 G173 P180 G181 V182 A183 I185
Binding residue
(residue number reindexed from 1)		L168 A169 G170 P177 G178 V179 A180 I182
Annotation score3
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004519 endonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0030955 potassium ion binding
GO:0046872 metal ion binding
GO:0048256 flap endonuclease activity
Biological Process
GO:0033567 DNA replication, Okazaki fragment processing

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Molecular Function
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Biological Process
External links
PDB RCSB:3zdc, PDBe:3zdc, PDBj:3zdc
PDBsum3zdc
PubMed23821668
UniProtQ8X6R9|XNI_ECO57 Flap endonuclease Xni (Gene Name=xni)

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