Structure of PDB 3zdb Chain A Binding Site BS02

Receptor Information
>3zdb Chain A (length=246) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDD
SSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEAD
DLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFI
DKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIY
ENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain3zdb Chain A Residue 1251 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zdb The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Resolution1.47 Å
Binding residue
(original residue number in PDB)		L171 A172 G173 P180 G181 V182 A183 I185 G186
Binding residue
(residue number reindexed from 1)		L167 A168 G169 P176 G177 V178 A179 I181 G182
Annotation score3
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004519 endonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0030955 potassium ion binding
GO:0046872 metal ion binding
GO:0048256 flap endonuclease activity
Biological Process
GO:0033567 DNA replication, Okazaki fragment processing

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Molecular Function
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Biological Process
External links
PDB RCSB:3zdb, PDBe:3zdb, PDBj:3zdb
PDBsum3zdb
PubMed23821668
UniProtQ8X6R9|XNI_ECO57 Flap endonuclease Xni (Gene Name=xni)

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