Structure of PDB 3zd7 Chain A Binding Site BS02

Receptor Information
>3zd7 Chain A (length=623) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKF
PQGQKGKVVFFANQIPVYEQNKSVFSKYFERHGYRVTGISGATAVPVEQI
VENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIM
FNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNTDEALDYICKLCASLDAS
VIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAK
RICKDLENLSQSQNREFGTQKYEQWIVTVQKACMSRICKALFLYTSHLRK
YNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQEL
ESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWI
EGNPKLSFLKPGILTNILILTSVADEGIDIAQCNLVILYEYVGNARGSKC
FLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEK
FIRDSKENKKLLCRKCKALACYTADVRVIEDCHYTVLGDAFKECFVSRPH
PKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDT
GVQTLYSKWKDFHFEKIPFDPAE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3zd7 Defining the Functional Determinants for RNA Surveillance by Rig-I.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Q299 I300 S325 G326 T347 Q349 N353 F853
Binding residue
(residue number reindexed from 1)		Q64 I65 S90 G91 T110 Q112 N116 F556
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:3zd7, PDBe:3zd7, PDBj:3zd7
PDBsum3zd7
PubMed23897087
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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