Structure of PDB 3x1d Chain A Binding Site BS02

Receptor Information
>3x1d Chain A (length=381) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSAVQVINASEEHTFVLNEDALSEVLMRDEVKDRFVCVVSVAGAFRKGKS
FLLDFFLRYMYSKYVHHDATERDTTGILMWSDIFLHDYPNGDKIAIILLD
TQGAFDCATVFALSTMLSSVQIYNLSQNIQEDDLQHLQLFTEYGRLALAD
TGKKPFQRLQFLVRDWSFPYEAEYGALGGDKILKRRLEVSDKQHPELQSL
RRHISSCFTEVACFLMPHPGLNVATNPKFDGRLQDITPEFKSSLRSLVPM
LLAPDNLVYKEISGQRVRARDLIQYFQSYMNIYKGNELPEPKSMLVATAE
ANHLTAVAAAKELYGQLMEEVCGGTRPYLSTAHLQTEHLRVKDKALFQFA
AKRKMGGEEFTEKFRKQLEDDLEEVFTNYQA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3x1d Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3x1d Comparison of human and Drosophila atlastin GTPases
Resolution2.87 Å
Binding residue
(original residue number in PDB)		K51 S52
Binding residue
(residue number reindexed from 1)		K49 S50
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0030742 GTP-dependent protein binding
GO:0032561 guanyl ribonucleotide binding
GO:0042802 identical protein binding
GO:0140506 endoplasmic reticulum-autophagosome adaptor activity
Biological Process
GO:0007019 microtubule depolymerization
GO:0007029 endoplasmic reticulum organization
GO:0007030 Golgi organization
GO:0007517 muscle organ development
GO:0007528 neuromuscular junction development
GO:0008582 regulation of synaptic assembly at neuromuscular junction
GO:0016320 endoplasmic reticulum membrane fusion
GO:0031114 regulation of microtubule depolymerization
GO:0048691 positive regulation of axon extension involved in regeneration
GO:0051124 synaptic assembly at neuromuscular junction
GO:0051260 protein homooligomerization
GO:0061025 membrane fusion
GO:0061709 reticulophagy
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0012505 endomembrane system
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3x1d, PDBe:3x1d, PDBj:3x1d
PDBsum3x1d
PubMed25407413
UniProtQ9VC57|ATLAS_DROME Atlastin (Gene Name=atl)

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