Structure of PDB 3wvv Chain A Binding Site BS02

Receptor Information

>3wvv Chain A (length=173) Species: 9796 (Equus caballus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SSQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALCGVAHF
FRELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAI
VLEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTN
IQRLVGSQAGLGEYLFERLTLKH

Ligand information

Ligand ID

InChI

InChI=1S/Ru/q+3

InChIKey

BPEVHDGLPIIAGH-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Ru+3]

Formula

Name

RUTHENIUM ION

ChEMBL

DrugBank

ZINC

PDB chain

3wvv Chain A Residue 215 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3wvv Intracellular CO release from composite of ferritin and ruthenium carbonyl complexes.
Resolution	1.82 Å
Binding residue (original residue number in PDB)	C45 H49
Binding residue (residue number reindexed from 1)	C45 H49
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005506	iron ion binding
GO:0008198	ferrous iron binding
GO:0008199	ferric iron binding
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion

	Cellular Component
GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005776	autophagosome
GO:0031410	cytoplasmic vesicle
GO:0044754	autolysosome
GO:0070288	ferritin complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:3wvv, PDBe:3wvv, PDBj:3wvv
PDBsum	3wvv
PubMed	25352251
UniProt	P02791\|FRIL_HORSE Ferritin light chain (Gene Name=FTL)

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