Structure of PDB 3w6p Chain A Binding Site BS02

Receptor Information
>3w6p Chain A (length=333) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPMEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGR
DLLPRGTGIVTRRPLILQLVHVSQEWGKFLHTKNKLYTDFDEIRQEIENE
TERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIEL
QIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVI
TKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRD
EYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQ
YQSLLRRKEAADMLKALQGASQIIAEIRETHLW
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain3w6p Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3w6p Crystal structure of GTPase domain fused with minimal stalks from human dynamin-1-like protein (Dlp1) in complex with several nucleotide analogues
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Q34 S35 K38 V58 T59 G149
Binding residue
(residue number reindexed from 1)		Q36 S37 K40 V60 T61 G135
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.5: dynamin GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3w6p, PDBe:3w6p, PDBj:3w6p
PDBsum3w6p
PubMed
UniProtO00429|DNM1L_HUMAN Dynamin-1-like protein (Gene Name=DNM1L)

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