Structure of PDB 3vpb Chain A Binding Site BS02

Receptor Information
>3vpb Chain A (length=281) Species: 273063 (Sulfurisphaera tokodaii str. 7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVVLIVDIVRQEEKLIAKALEENKVQYDIINVAQEPLPFNKALGRYDVA
IIRPVSMYRALYSSAVLEAAGVHTINSSDVINVCGDKILTYSKLYREGIP
IPDSIIALSAEAALKAYEQRGFPLIDKPPIGSWGRLVSLIRDVFEGKTII
EHRELMGNSALKAHIVQEYIQYKGRDIRCIAIGEELLGCYARNIPPNEWR
ANVALGGTPSNIEVDEKLKETVVKAVSIVHGEFVSIDILEHPNKGYVVNE
LNDVPEFKGFMVATNINVAQKLVEYIKENYS
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain3vpb Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3vpb Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus
Resolution1.8 Å
Binding residue
(original residue number in PDB)		Y190 R192 N202 V203 A204 E256 G259 F260
Binding residue
(residue number reindexed from 1)		Y190 R192 N202 V203 A204 E256 G259 F260
Annotation score5
Enzymatic activity
Enzyme Commision number 6.3.2.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0042802 identical protein binding
GO:0043774 coenzyme F420-2 alpha-glutamyl ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006526 L-arginine biosynthetic process
GO:0009085 lysine biosynthetic process
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vpb, PDBe:3vpb, PDBj:3vpb
PDBsum3vpb
PubMed23434852
UniProtQ970U6|ARGX_SULTO Glutamate--LysW ligase ArgX (Gene Name=argX)

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