Structure of PDB 3vl3 Chain A Binding Site BS02
Receptor Information
>3vl3 Chain A (length=364) Species:
211586
(Shewanella oneidensis MR-1) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SSYQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDN
HGCPLPEATLKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHF
ELFCNLRPAKLHDGLEHMSPLRSDISARGFDVLCVRELTGGIYFGKPKGR
QGEGESEEAFDTMRYSRREISRIARIAFEAARGRRKKVTSVDKANVLACS
VLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDI
LSDEIAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQI
LSAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQRHKAKTTV
QMGDFIADAVKAGV
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
3vl3 Chain A Residue 402 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3vl3
High-pressure-induced water penetration into 3-isopropylmalate dehydrogenase
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
D249 D253
Binding residue
(residue number reindexed from 1)
D249 D253
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
Y143 K193 D225 D249 D253
Catalytic site (residue number reindexed from 1)
Y143 K193 D225 D249 D253
Enzyme Commision number
1.1.1.85
: 3-isopropylmalate dehydrogenase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0003862
3-isopropylmalate dehydrogenase activity
GO:0016491
oxidoreductase activity
GO:0016616
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872
metal ion binding
GO:0051287
NAD binding
Biological Process
GO:0009098
L-leucine biosynthetic process
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:3vl3
,
PDBe:3vl3
,
PDBj:3vl3
PDBsum
3vl3
PubMed
22349232
UniProt
Q8E9N3
|LEU3_SHEON 3-isopropylmalate dehydrogenase (Gene Name=leuB)
[
Back to BioLiP
]