Structure of PDB 3veo Chain A Binding Site BS02

Receptor Information
>3veo Chain A (length=571) Species: 1933 (Streptoalloteichus tenebrarius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMRVLGLNGWPRDFHDASAALLVDGRIAAFAEEERLTRKKHGYNTAPVQA
AAFCLAQAGLTVDDLDAVAFGWDLPAMYRERLGGWPHSDSEALDILLPRD
VFPRRTDPPLHFVQHHLAHAASAYYFSGEDRGAVLIVDGQGEEECVTLAH
AEGGKITVLDTVPGAWSLGFFYEHVSEYTGLGGDNPGKLMGLAAHGTTVD
ETLSAFAFDSDGYRLNLIDPQARDPEDWDEYSVTERAWFAHLERIYRLPP
NEFVRRYDPAKGRVVRDTRRDPYEYRDLAATAQAALERAVFGLADSVLAR
TGERTLFVAGGVGLNATMNGKLLTRSTVDKMFVPPVASDIGVSLGAAAAV
AVELGDRIAPMGDTAAWGPEFSPDQVRAALDRTGLAYREPANLEREVAAL
IASGKVVGWAQGRGEVGPRALGQRSLLGSAHSPTMRDHINLRVKDREWWR
PFAPSMLRSVSDQVLEVDADFPYMIMTTKVRAAYAERLPSVVHEDWSTRP
QTVTEASNPRYHRMLTELGDLVGDPVCLNTSFNDRGEPIVSSPADALLTF
SRLPIDALAVGPYLVTKDLRH
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain3veo Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3veo The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.
Resolution2.187 Å
Binding residue
(original residue number in PDB)		H114 H118 D137 D338
Binding residue
(residue number reindexed from 1)		H115 H119 D138 D339
Annotation score1
Enzymatic activity
Enzyme Commision number 6.1.2.2: nebramycin 5' synthase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005506 iron ion binding
GO:0005524 ATP binding
GO:0016743 carboxyl- or carbamoyltransferase activity
GO:0016787 hydrolase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0009058 biosynthetic process
GO:0017000 antibiotic biosynthetic process
GO:1901121 tobramycin biosynthetic process
GO:1901133 kanamycin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3veo, PDBe:3veo, PDBj:3veo
PDBsum3veo
PubMed22383337
UniProtQ70IY1|TOBZ_STRSD nebramycin 5' synthase (Gene Name=tobZ)

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