Structure of PDB 3v43 Chain A Binding Site BS02

Receptor Information
>3v43 Chain A (length=112) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVR
VKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMP
KGMWICQICRPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3v43 Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3v43 Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
Resolution1.47 Å
Binding residue
(original residue number in PDB)		C281 C284 C307 C310
Binding residue
(residue number reindexed from 1)		C80 C83 C106 C109
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
External links
PDB RCSB:3v43, PDBe:3v43, PDBj:3v43
PDBsum3v43
PubMed22713874
UniProtQ92794|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)

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