Structure of PDB 3us9 Chain A Binding Site BS02

Receptor Information
>3us9 Chain A (length=249) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSD
YEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDKNFLVHLSNVKVSSEALA
CLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGN
VIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKN
KTFFLEIGEPRLVEMTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3us9 Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3us9 A common Ca2+-driven interdomain module governs eukaryotic NCX regulation.
Resolution2.68 Å
Binding residue
(original residue number in PDB)		E385 D446 D447 D499 D500
Binding residue
(residue number reindexed from 1)		E14 D75 D76 D115 D116
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007154 cell communication
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:3us9, PDBe:3us9, PDBj:3us9
PDBsum3us9
PubMed22768191
UniProtP23685|NAC1_CANLF Sodium/calcium exchanger 1 (Gene Name=SLC8A1)

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