Structure of PDB 3um1 Chain A Binding Site BS02

Receptor Information
>3um1 Chain A (length=375) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
THWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDLS
CNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVP
SAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAA
GIFKHLKESHLPKLITPAEKGRDLESRLIEAYVIQCQAEAQEVTIARAIE
LKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTA
YAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPTV
KPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKIPTEAPQLELKANYGLV
EPIPFEFPPTSVQWTPETLAAFDLT
Ligand information
Receptor-Ligand Complex Structure
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PDB3um1 Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Resolution2.708 Å
Binding residue
(original residue number in PDB)		A205 G207 L208 N347 Y348
Binding residue
(residue number reindexed from 1)		A204 G206 L207 N346 Y347
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007084 mitotic nuclear membrane reassembly
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3um1, PDBe:3um1, PDBj:3um1
PDBsum3um1
PubMed22484091
UniProtQ5VW32|BROX_HUMAN BRO1 domain-containing protein BROX (Gene Name=BROX)

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