Structure of PDB 3ukm Chain A Binding Site BS02

Receptor Information
>3ukm Chain A (length=252) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSATMFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEH
ECLSEQQLEQFLGRVLEASNYGVSVLWNWDFTSALFFASTVLSTTGYGHT
VPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFSKQVV
AIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLG
DYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKM
FY
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain3ukm Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ukm Crystal structure of the human two-pore domain potassium channel K2P1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		T118 G119 Y120 I226 G227 L228
Binding residue
(residue number reindexed from 1)		T95 G96 Y97 I197 G198 L199
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ukm, PDBe:3ukm, PDBj:3ukm
PDBsum3ukm
PubMed22282804
UniProtO00180|KCNK1_HUMAN Potassium channel subfamily K member 1 (Gene Name=KCNK1)

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