Structure of PDB 3ug6 Chain A Binding Site BS02

Receptor Information
>3ug6 Chain A (length=303) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIVSTDPAHSLRDIFE
QEFGHEPTKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEENPFLGEMLED
QLEMAALSPGTDESAAFDVFLKYMDSNEFDVVIFDTAPTGHTLRFLGMPE
VMDKYMTKLIKLRKQMSGFMKMMKKLLPFDYDKMLEELEKMKERIVRARN
ILSDPERTAFRLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQLIPED
VQCDFCRARRELQLKRLEMIKEKFGDKVIAYVPLLRTEAKGIETLKQIAK
ILY
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3ug6 Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ug6 Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		T40 D63
Binding residue
(residue number reindexed from 1)		T17 D40
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G36 G38 K39 T40 T41 D63
Catalytic site (residue number reindexed from 1) G13 G15 K16 T17 T18 D40
Enzyme Commision number 7.3.2.7: arsenite-transporting ATPase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015446 ATPase-coupled arsenite transmembrane transporter activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0046685 response to arsenic-containing substance
GO:0071722 detoxification of arsenic-containing substance

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Molecular Function
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Biological Process
External links
PDB RCSB:3ug6, PDBe:3ug6, PDBj:3ug6
PDBsum3ug6
PubMed22124326
UniProtQ58542|ARSA_METJA Putative arsenical pump-driving ATPase (Gene Name=MJ1142)

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