Structure of PDB 3s57 Chain A Binding Site BS02

Receptor Information
>3s57 Chain A (length=204) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRG
KSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFR
KILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3s57 Duplex interrogation by a direct DNA repair protein in search of base damage
Resolution1.6 Å
Binding residue
(original residue number in PDB)		Q100 F102 R176 K205 R241 K242 K243
Binding residue
(residue number reindexed from 1)		Q46 F48 R122 K151 R187 K188 K189
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3s57, PDBe:3s57, PDBj:3s57
PDBsum3s57
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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