Structure of PDB 3s29 Chain A Binding Site BS02

Receptor Information
>3s29 Chain A (length=781) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEVLALLSRVEAKGKGILQQNQIIAEFEALPEQTRKKLEGGPFFDLLKST
QEAIVLPPWVALAVRPRPGVWEYLRVNLHALVVEELQPAEFLHFKEELVD
GVKNGNFTLELDFEPFNASIPRPTLHKYIGNGVDFLNRHLSAKLFHDKES
LLPLLKFLRLHSHQGKNLMLSEKIQNLNTLQHTLRKAEEYLAELKSETLY
EEFEAKFEEIGLERGWGDNAERVLDMIRLLLDLLEAPDPCTLETFLGRVP
MVFNVVILSPHGYFAQDNVLGYPDTGGQVVYILDQVRALEIEMLQRIKQQ
GLNIKPRILILTRLLPDAVGTTCGERLERVYDSEYCDILRVPFRTEKGIV
RKWISRFEVWPYLETYTEDAAVELSKELNGKPDLIIGNYSDGNLVASLLA
HKLGVTQCTIAHALEKTKYPDSDIYWKKLDDKYHFSCQFTADIFAMNHTD
FIITSTFQEIAGSKETVGQYESHTAFTLPGLYRVVHGIDVFDPKFNIVSP
GADMSIYFPYTEEKRRLTKFHSEIEELLYSDVENKEHLCVLKDKKKPILF
TMARLDRVKNLSGLVEWYGKNTRLRELANLVVVGGDRRKESKDNEEKAEM
KKMYDLIEEYKLNGQFRWISSQMDRVRNGELYRYICDTKGAFVQPALYEA
FGLTVVEAMTCGLPTFATCKGGPAEIIVHGKSGFHIDPYHGDQAADTLAD
FFTKCKEDPSHWDEISKGGLQRIEEKYTWQIYSQRLLTLTGVYGFWKHVS
NLDRLEARRYLEMFYALKYRPLAQAVPLAQD
Ligand information
Ligand IDFRU
InChIInChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKeyRFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
FormulaC6 H12 O6
Namebeta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBLCHEMBL604608
DrugBank
ZINCZINC000001529270
PDB chain3s29 Chain A Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3s29 The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		G302 Q304 R382 R580
Binding residue
(residue number reindexed from 1)		G276 Q278 R356 R554
Annotation score5
Enzymatic activity
Enzyme Commision number 2.4.1.13: sucrose synthase.
Gene Ontology
Molecular Function
GO:0016157 sucrose synthase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0001666 response to hypoxia
GO:0005985 sucrose metabolic process
GO:0006970 response to osmotic stress
GO:0009409 response to cold
GO:0009413 response to flooding
GO:0009414 response to water deprivation
GO:0009744 response to sucrose
GO:0009749 response to glucose
GO:0010555 response to mannitol
GO:0071456 cellular response to hypoxia
GO:0072708 response to sorbitol
Cellular Component
GO:0005829 cytosol
GO:0009506 plasmodesma

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3s29, PDBe:3s29, PDBj:3s29
PDBsum3s29
PubMed21865170
UniProtP49040|SUS1_ARATH Sucrose synthase 1 (Gene Name=SUS1)

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